Titel
Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery Platform
Autor*in
Ryan A. Miller
Department of Bioinformatics (BiGCaT), Maastricht University
Autor*in
Peter Woollard
GlaxoSmithKline (GSK)
Autor*in
Egon L. Willighagen
Department of Bioinformatics (BiGCaT), Maastricht University
... show all
Abstract
Open PHACTS is a pre-competitive project to answer scientific questions developed recently by the pharmaceutical industry. Having high quality biological interaction information in the Open PHACTS Discovery Platform is needed to answer multiple pathway related questions. To address this, updated WikiPathways data has been added to the platform. This data includes information about biological interactions, such as stimulation and inhibition. The platform's Application Programming Interface (API) was extended with appropriate calls to reference these interactions. These new methods of the Open PHACTS API are available now.
Stichwort
Open PHACTSdrug discoverysemanticbioinformaticsWikiPathwayspathway databaseAPI
Objekt-Typ
Sprache
Englisch [eng]
Persistent identifier
https://phaidra.univie.ac.at/o:1032861
Erschienen in
Titel
F1000Research
Band
7
Seitenanfang
75
Verlag
F1000 ( Faculty of 1000 Ltd)
Erscheinungsdatum
2018
Zugänglichkeit
Rechteangabe
© 2018 Miller RA et al

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