This paper summarises the half-day workshop on national and regional portals, organised by the RIS Synergy project for the CRIS2022 conference. The goal of the workshop was to discuss challenges and opportunities of national and regional research portals with representatives of six different portals and implementation projects. In an expert panel talk, participants shared their experiences with the initiation and implementation of their national/regional portal. Moderated questions also addressed various topics such as target groups, stakeholders, technical specifications and standards. The workshop contributes to the international collaboration of research portal operators and promotes the exchange of lessons learned.