Titel
DARIO: a ncRNA detection and analysis tool for next-generation sequencing experiments
Autor*in
Mario Fasold
Universität Leipzig
Autor*in
David Langenberger
Universität Leipzig
Autor*in
Hans Binder
Universität Leipzig
... show all
Abstract
Small non-coding RNAs (ncRNAs) such as microRNAs, snoRNAs and tRNAs are a diverse collection of molecules with several important biological functions. Current methods for high-throughput sequencing for the first time offer the opportunity to investigate the entire ncRNAome in an essentially unbiased way. However, there is a substantial need for methods that allow a convenient analysis of these overwhelmingly large data sets. Here, we present DARIO, a free web service that allows to study short read data from small RNA-seq experiments. It provides a wide range of analysis features, including quality control, read normalization, ncRNA quantification and prediction of putative ncRNA candidates. The DARIO web site can be accessed at http://dario.bioinf.uni-leipzig.de/.
Objekt-Typ
Sprache
Englisch [eng]
Persistent identifier
https://phaidra.univie.ac.at/o:245695
Erschienen in
Titel
Nucleic Acids Research
Band
39
Ausgabe
Supp 2
Seitenanfang
W112
Seitenende
W117
Erscheinungsdatum
01.09.2011
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